H3K36me2 is highly correlated with m6A modifications in plantsFA

• 作者: Hong Gil Lee Hongwoo Lee Pil Joon Seo Sangrea Shim
• 来源期刊: 植物学报（英文版）
• 年，卷（期）: 2020,（10）
• 页码范围: 1455-1460
• 页数: 6页
• 语种: 英文
• DOI: 10.1111/jipb.12917

摘要

Various chemical modifications at the nucleosome, including DNA methylation, histone H3 acetylation (H3Ac), and histone H3 mono-/di-/trimethylation at various lysine residues (H3K4me3, H3K9me1/me2, H3K27me3, and H3K36me2/me3), underlie the delicate control of chromatin architecture (Ramirez-Prado et al. 2018). These modifications influence gene ex-pression by changing the accessibility of chromatin by RNA Pol Ⅱ and chromatin-binding proteins, under-pinning the importance of chromatin landscape in gene regulation (Malapeira et al. 2012).