Heat-Clearing Chinese Medicines in Lipopolysaccharide-Induced Inflammation

• 来源期刊: 中国结合医学杂志（英文版）
• 年，卷（期）: 2020,（7）
• 页码范围: 552-559
• 页数: 8页
• 语种: 英文
• DOI: 10.1007/s11655-020-3256-7

摘要

Lipopolysaccharide (LPS)-induced inflammation causes massive threatening diseases,such as sepsis,acute lung injury and multiple organ dysfunction syndrome.Efficient treatment to prevent inflammation is crucial in LPS-induced inflammatory diseases.Heat-clearing Chinese medicines (CMs) have been used to ameliorate LPS-induced inflammation in China for centuries.Heat-clearing CMs regulate inflammatory pathways,thereby inhibiting the release of inflammatory factors.This review aimed to introduce promising heat-clearing CMs countering LPS-induced inflammation in the last 5 years,exploring the underlying molecular mechanisms.