Pancreatoblastoma: A rare indication for liver transplantation in children

• 作者: Anil Dhawan Hector Vilca-Melendez Maria Mercadal-Hally Nigel Heaton Sucheta Vaidya Tassos Grammatikopoulos
• 来源期刊: 国际肝胆胰疾病杂志(英文版)
• 年，卷（期）: 2020,（5）
• 页码范围: 499-501
• 页数: 3页
• 语种: 英文

摘要

To the Editor : Pancreatoblastoma (PB) is one of the exocrine pancreatic tu- mors and the most common malignant pancreatic tumor in young children. Patients can present with abdominal distension, pain, fa- tigue, vomiting and failure to thrive. Exocrine pancreatic tumors usually affect patients between 1 and 8 years, with a median age of 5 years. There is a slight preponderance in males and those of Asian descent [1] . PB is considered to be embryonic in origin with moderately raised serum alpha-fetoprotein (AFP) levels [2] . Axial imaging is necessary to assess other organ involvement, a common complication in adult patients, but diagnosis is confirmed on tissue histology [3] . Complete surgical resection is the treat- ment of choice, if achievable. Indications for neoadjuvant systemic chemotherapy include large tumors that involve adjacent major blood vessels or other organs and metastatic disease [1] . Herein we report a pediatric case of PB with liver metastases who underwent liver transplantation for metastatic liver disease.