Microscopic Features, Antioxidant and Antibacterial Capacities of Plants of the Congolese Cosmetopoeia, Raw Materials of Cosmeceuticals

• 作者: Boniface Nlandu Lukebakio Carmel Kandhe Gabha’Bey Cyprien Mbundu Lukukula Didi Mana Kialengila Dorcas Mukundi Lukusa Isaac Kaba Elaka Jonathan Mukanya Mpoyi Messie Muipata Muabilwa Monique Kandolo Okuna Nadège Kabamba Ngombe Paul Tshilumbu Kantola Paulin Mutwale Kapepula
• 来源期刊: 生物科学与医学(英文)
• 学科: 医学
• 关键词: Cannabis sativa Chromolaena odorata COSMECEUTICALS Cosmetopoeia Mitracarpus villosus Pterocarpus soyauxii Senna alata Tetradenia riparia Yelena
• 年，卷（期）: 2020,（9）
• 页码范围: 149-166
• 页数: 18页
• 分类号: R28

摘要

Cosmeceuticals are the fastest growing products in the cosmetics field and represent a hybrid between cosmetics and drugs. The main benefits reported for cosmeceutical herbal extracts, used in skin care, include antioxidant and antimicrobial activities and the tyrosinase inhibiting effect. The aim of this study was to evaluate the antioxidant and antibacterial activities of extracts from <em>Chromolaena odorata, Mitracarpus villosus, Senna alata, Tetradenia riparia, Cannabis sativa</em> and <em>Pterocarpus soyauxii</em> used traditionally in the management of skin and skin annexes pathologies;additionally to determine their microscopical characteristics and their chromatographic fingerprints. Microscopic analyses showed the specific botanical microscopic characters for each plant that constitute the database useful for the identification and authentication of these botanicals. To the best of our knowledge, our work is the first to describe the microscopic histological characters of studied plants except for <em>Cannabis sativa</em>. The results of the TLC chromatographic analysis revealed the richness in phenolic compounds, terpenes in all extracts and <em>Pterocarpus soyauxii </em>contained coumarins. All extracts displayed high ABTS and DPPH radical-scavenging activities connected with their IC₅₀ values at the concentration range of 1 - 125 μg/mL with<em> Cannabis sativa</em> and <em>Pterocarpus soyauxii </em>as the most active. All plant extracts exhibited antibacterial activity on<em> Escherichia coli</em>, <em>Pseudomonas aeruginosa</em> and <em>Staphylococcus aureus</em> to varying degrees. Cannabis sativa exhibited strong effect on <em>Staphylococcus aureus</em> and <em>Escherichia coli</em>. <em>Chromolaena odorata</em> and <em>Tetradenia riparia </em>showed a marked effect on <em>Escherichia coli</em>. Although certain crude extracts from studied botanicals have been shown to be inactive, fractionation studies are needed to determine the active fractions. Obtained biological activities could