An unexpected iron(Ⅱ)-promoted reaction of N-arylprop-2-yn-1-imines with water: Facile assembly of multi-substituted pyrroles

• 来源期刊: 中国化学快报（英文版）
• 年，卷（期）: 2021,（1）
• 所属期刊栏目: Communications
• 页码范围: 37-39
• 页数: 3页
• 语种: 英文

摘要

Generation of multi-substituted pyrroles is accomplished through an unexpected iron(Ⅱ)-promoted reaction of N-arylprop-2-yn-1-imines with water. This transformation proceeds smoothly with excellent chemoselectivity and regioselectivity. A stoichiometric amount of Fe(Otf)2 is necessary for the successful conversion. A Lewis acid-promoted tandem reaction pathway is proposed.