The Systemic Inflammation on Transradial vs Transfemoral Approach for Coronary Angiography in Patients with Chronic Coronary Syndrome <br/>—Does Transradial Coronary Angiography Trigger More Inflammation?

• 作者: Ozge Cetinarslan Aysem Kaya Alev Arat Ozkan
• 来源期刊: 心血管病(英文)
• 学科: 医学
• 关键词: Transradial Coronary Angiography Transfemoral Coronary Angiography INFLAMMATION TNFΑ hs-CRP
• 年，卷（期）: 2021,（2）
• 页码范围: 99-105
• 页数: 7页
• 分类号: R54

摘要

<strong>Background:</strong> <span style="font-family:;" "=""><span style="font-family:Verdana;">Most of the institutions accept the Transradial Access (TRA) as the first approach for patients undergoing Coronary Angiography (CAG) and Percutaneous Coronary Interventions (PCI). Several studies clearly revealed endothelial injury of coronary arteries triggers inflammatory response. In this study, we aimed to evaluate inflammatory respond to CAG and to compare the inflammatory response of TRA and Transfemoral Access (TFA). </span><b><span style="font-family:Verdana;">Methods: </span></b><span style="font-family:Verdana;">In this single-center prospective study 140 consecutive patients presenting with (Chronical Coronary Syndrome) CCS and underwent transradial or transfemoral CAG between December 2017 and December 2018 were included. After exclusions, left 92 patients were divided into two equal groups as TRA and TFA. The primary endpoints were 2nd hour Tumor Necrosis Factor alpha (TNF</span><i><span style="font-family:Verdana;">α</span></i><span style="font-family:Verdana;">), 48</span>^{<span style="font-size:12px;font-family:Verdana;">th</span>}<span style="font-family:Verdana;"> hour high-sensitivity C-Reactive Protein</span></span><span style="font-family:Verdana;"> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">(hs-CRP), complication rates, amount of contrast medium, procedure time and fluoroscopy time. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">Basal characteristics of TRA and TFA groups were similar. A comparison of variables demonstrated that there was no statistical significance in increase in inflammatory markers (TNF</span><i><span style="font-family:Verdana;">α</span></i><span style="font-family:Verdana;">, hs-CRP), complication rates, amount of contrast media and procedure time. In contrast, TRA was associated longer fluoroscopy time and higher X-ray dosage, although statistically insignificant. CAG caused a s