Happy Hypoxia in COVID-19 Patients at Kinshasa University Hospital (Democratic Republic of the Congo): Frequency and Vital Outcome

• 作者: Ben Bepouka Hippolyte Situakibanza Ossam Odio Jean Robert Makulo Madone Mandina Murielle Longokolo Nadine Mayasi Kazadi Mutombo Tresor Pata Godelive Nsangana Felly Tshikangu Donatien Mangala Dupont Maheshe Christine Namasale Serge Nkarnkwin Jonathan Muamba Gorby Ndaie Rodrigue Ngwizani Hervé Mole Gabriel Makeya Tharcisse Mabiala Patrick Mukuna Roger Kabango Patricia Kabuni Yves Yanga Aliocha Nkodila Hervé Keke Nice Musangu Papy Tshimanga Yamin Kokusa Bertin Nsitwayizatadi Eric Mukenge Guyguy Kamwiziku Gabriel Mbunsu Jean Claude Makangara Marcel Mbula Jean Marie Kayembe
• 来源期刊: 生物科学与医学(英文)
• 学科: 医学
• 关键词: COVID-19 Happy Hypoxia FREQUENCY OUTCOME DR Congo
• 年，卷（期）: 2021,（2）
• 页码范围: 12-20
• 页数: 9页
• 分类号: R73

摘要

<strong>Background: </strong>Happy hypoxia is a new feature found in COVID-19 patients. It consists of the presence of severe hypoxemia but normal breathing rate. Failure to identify this hypoxia may have negative consequences on the survival of the patient. The objective of the present study was to measure the frequency of patients with happy hypoxia and to evaluate their survival at the Kinshasa University Hospital (KUH). <strong>Methods: </strong>This was a historical cohort of 141 hospitalized patients with COVID-19 at KUH from March 23 to June 15, 2020. Happy hypoxia was defined as oxygen saturation below 90% without dyspnea. Socio-demographic data, co-morbidities, follow up time of hospitalization and outcomes were studied. Survival was assessed using the Kaplan Meier curve. <strong>Results:</strong> Out of 141 hospitalized patients with COVID-19, 79 (56%) patients were at the severe or critical stage and 9 (6.4%) had a happy hypoxia on admission. Patients who had happy hypoxia on admission were generally older than 60 years of age (55.6%) (p = 0.023). Comparison of survival curves, based on the presence or absence of happy hypoxia, shows a statistically significant difference (p = 0.001). The presence of happy hypoxia reduces survival. <strong>Conclusion:</strong> The frequency of happy hypoxia among COVID-19 patients was low. Survival was reduced in patients with happy hypoxia. Prehospital pulse oximetry could serve as an early warning signal for the detection of happy hypoxemia in COVID-19 patients.