Neurocysticercosis is the most common neuro-parasitosis caused by the larval stage of Taenia solium.The most common manifestations include seizures and hydrocephalus.Psychiatric abnormalities are relatively rare but depressive symptoms are frequent in patients with neurocysticercosis.However,mania as a presentation is relatively rare.Pregnancy and the postpartum period are relatively vulnerable times and they can lead to reactivation of existing neurocysterci lesions.We are discussing the case of a 23-year-old female patient with neurocysticercosis leading to the reactivation of lesions in the peripartum and postpartum period leading to bipolar affective disorder.Improvement in the patient was seen with a combination of antipsychotics,antihelmintics,antiepileptics and steroids,along with improved radiological signs of neurocysterci lesions.Although neurocysticercosis is a common illness,its prevalence presenting as a manic episode is merely 2.6%and,hence,missed easily.Therefore,it is important to rule out organic aetiology in patients even with a classic presentation of bipolar affective disorder and those having any other neurological symptoms and signs.