The anisotropy of thermal property in an Yb,Nd∶ Sc2SiC5 crystal is investigated from the temperature of 293 to 573 K.Based on the systematical study of thermal expansion,thermal diffusivity,and specific heat,the thermal conductivity in Yb,Nd∶Sc2SiC5 crystals orientated at[100],[010],[001],and[406]is calculated to be 3.46,2.60,3.35,and 3.68 W/(m· K),respectively.The laser output anisotropy of a continuous-wave[CW]and tunable laser is characterized,accordingly.A maximum output power of 6.09 W is achieved in the Yb,Nd∶ Sc2SiC5 crystal with[010]direction,corresponding to a slope efficiency of 48.56%.The tuning wavelength range in the Yb,Nd∶ Sc2SiC5 crystal orientated at[100],[010],and[001]is 68,67,and 65 nm,separately.The effects of thermal properties on CW laser performance are discussed.