Functional Striatal Abnormalities:A Distinct Brain Signature of Schizophrenia

• 来源期刊: 神经科学通报（英文版）
• 年，卷（期）: 2021,（2）
• 所属期刊栏目: Research Highlights
• 页码范围: 284-286
• 页数: 3页
• 语种: 英文

摘要

Schizophrenia is a severe and complex mental disorder[1].Neuroimaging offers a powerful window for identifying the brain biomarkers and investigating the neuropathological mechanisms of psychiatric disorders.A study led by Professors Jiang and Liu,published recently in Nature Medicine,developed a new neuroimaging biomarker to characterize striatal dysfunction based on a multi-site functional MRI dataset with＞1000 individuals.They show that this biomarker can distinguish individuals with schizophrenia and predict the short-term effects of antipsy-chotic treatment[2].