Restricted Feeding Resets Endogenous Circadian Rhythm in Female Mice Under Constant Darkness

• 作者: Yue Mei Huajing Teng Zhigang Li Cheng Zeng Yuanyuan Li Wei Song Kaifan Zhang Zhong Sheng Sun Yan Wang
• 来源期刊: 神经科学通报（英文版）
• 年，卷（期）: 2021,（7）
• 所属期刊栏目: Letters to the Editor
• 页码范围: 1005-1009
• 页数: 5页
• 语种: 英文

摘要

Dear Editor, Circadian rhythms are driven by a complex,profoundly integrated network of clocks that maintain physiology and behaviors occurring at precise times and in the right order[1-3].Light,the most powerful zeitgeber,entrains the central clock in the suprachiasmatic nucleus(SCN)via the retinohypothalamic tract with a precise 24-h rhythm in mammals[4,5].Due to irregular exposure to light conditions,such as an arrhythmic lifestyle,jet lag,and shift-work,circadian disturbance occurs quite often in modern societies and promotes a series of health problems such as obesity,depression,and neurodegenerative dis-eases[6,7].