STING-ing Pain:How Can Pro-inflammatory Signaling Attenuate Pain?

• 作者: Wolfgang Liedtke
• 来源期刊: 神经科学通报（英文版）
• 年，卷（期）: 2021,（7）
• 所属期刊栏目: Research Highlights
• 页码范围: 1075-1078
• 页数: 4页
• 语种: 英文

摘要

Inflammation typically induces pain by producing pro-inflammatory mediators,but increasing evidence also indicates a role for inflammation in the resolution of pain by inducing anti-inflammatory and pro-resolution media-tors[1,2].A recent Nature paper from Duke University,"STING controls nociception via type-Ⅰ interferon signal-ing in sensory neurons",is noteworthy in this respect[3].