Our bodies contain a huge amount of anatomical,physiolo-gical,cellular or molecular information.The understanding of how these pieces of information are organized has a sig-nificant impact on the progress of biology and biomedicine.At present,fluorescence multiplexing approaches,such as immunofluorescence and fluorescence in situ hybridization(FISH),provide'snapshots' of a few biological species of interest (molecules,cells etc.) in fixed slice samples at once by using spectrally distinct fluorescent labels [1].