New progress of novel COVID-19 variants and its effect on vaccine immune protection

• 作者: Cai-Hong Wang Rong Wang Yu-Xia Zhou Xiao-Wen Yao Xiao-Hui Yu Jiu-Cong Zhang
• 来源期刊: 海南医科大学学报（英文版）
• 年，卷（期）: 2022,（6）
• 所属期刊栏目: Novel Coronavirus Column
• 页码范围: 1-5
• 页数: 5页
• 语种: 英文

摘要

The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses a serious threat to human life and health as well as social and economic development. In order to deal with this public health event, scientific research institutions around the world have rapidly developed and put vaccines into urgent use, bringing hope to the victory over the epidemic. However, as the Novel Coronavirus continues to spread throughout the world, the virus genome has mutated to form a variety of variants. Among them, the Alpha, Beta, Gamma, Delta and Omicron variants show higher infectivity and higher resistance to vaccines and neutralizing antibodies, posing new challenges to the prevention and treatment of COVID-19. At present, the effect of variants on the effectiveness of developed vaccines has become a hot topic of global discussion. In this paper, we briefly review the new progress of novel Coronavirus variants and their effects on vaccine immune protection.