A General Strategy for Efficiently Constructing Multifunctional Cluster Fillers Using a Three-Fluid Nozzle Spray Drying Technique for Dental Restoration

• 作者: Dan-Lei Yang Dan Wang Hao Niu Rui-Li Wang Mei Liu Fei-Min Zhang Jie-Xin Wang Mei-Fang Zhu
• 来源期刊: 工程（英文）
• 年，卷（期）: 2022,（1）
• 所属期刊栏目: Green Chemical Engineering-Article
• 页码范围: 138-147
• 页数: 10页
• 语种: 英文

摘要

Multifunctional fillers are greatly required for dental resin composites(DRCs).In this work,a spray dryer with a three-fluid nozzle was applied for the first time to construct high-performance complex nanopar-ticle clusters(CNCs)consisting of different functional nanofillers for dental restoration.The application of a three-fluid nozzle can effectively avoid the aggregation of different nanoparticles with opposite zeta potentials before the spray drying process in order to construct regularly shaped CNCs.For a SiO2-ZrO2 binary system,the SiO2-ZrO2 CNCs constructed using a three-fluid nozzle maintained their excellent mechanical properties((133.3±4.7)MPa,(8.8±0.5)GPa,(371.1±13.3)MPa,and(64.5±0.7)HV for flexu-ral strength,flexural modulus,compressive strength,and hardness of DRCs,respectively),despite the introduction of ZrO2 nanoparticles,whereas their counterparts constructed using a two-fluid nozzle showed significantly decreased mechanical properties.Furthermore,heat treatment of the SiO2-ZrO2 CNCs significantly improved the mechanical properties and radiopacity of the DRCs.The DRCs containing over 10％mass fraction ZrO2 nanoparticles can meet the requirement for radiopaque fillers.More impor-tantly,this method can be expanded to ternary or quaternary systems.DRCs filled with SiO2-ZrO2-ZnO CNCs with a ratio of 56∶10∶4 displayed high antibacterial activity(antibacterial ratio＞99％)in addition to excellent mechanical properties and radiopacity.Thus,the three-fluid nozzle spray drying technique holds great potential for the efficient construction of multifunctional cluster fillers for DRCs.