第5页_药学学报(英文版)2021年出版文献-钛学术文献服务平台

文献导航

检索期刊

出版文献量（篇）

688

总下载数（次）

药学学报(英文版)

投稿

Acta Pharmaceutica Sinica B

CSTPCD

影响因子 1.2053

ISSN：

2211-3835

CN：

10-1171/R

出版周期：

双月刊

邮编：

100050

地址：

北京市先农坛街1号

出版文献量（篇）

688

总下载数（次）

文章浏览

热门刊内文献

年度刊次

2022年
2021年

12期

11期

10期

7期

6期

5期

4期

3期

2期

1期
2020年
2019年
2018年
2017年
2016年
2015年

121. CRISPR-Cas9:A method for establishing rat models of drug metabolism and pharmacokinetics

作者： Jian Lu Jie Liu Yuanqing Guo Yuanjin Zhang Yeye Xu Xin Wang

刊名：药学学报(英文版)

发表期刊： 2021年10期

页码: 2973-2982

摘要： The 2020 Nobel Prize in Chemistry recognized CRISPR-Cas9,a super-selective and precise gene edi...
122. Alterations of DNA damage response pathway:Biomarker and therapeutic strategy for cancer immunotherapy

作者： Minlin Jiang Keyi Jia Lei Wang Wei Li Bin Chen Yu Liu Hao Wang Sha Zhao Yayi He Caicun Zhou

刊名：药学学报(英文版)

发表期刊： 2021年10期

页码: 2983-2994

摘要： Genomic instability remains an enabling feature of cancer and promotes malignant transfor-matio...
123. Natural compounds in the regulation of proteostatic pathways:An invincible artillery against stress,ageing,and diseases

作者： Arun Upadhyay

刊名：药学学报(英文版)

发表期刊： 2021年10期

页码: 2995-3014

摘要： Cells have different sets of molecules for performing an array of physiological functions.Nu-cl...
124. Targeting autophagy using small-molecule compounds to improve potential therapy of Parkinson's disease

作者： Kai Zhang Shiou Zhu Jiamei Li Tingting Jiang Lu Feng Junping Pei Guan Wang Liang Ouyang Bo Liu

刊名：药学学报(英文版)

发表期刊： 2021年10期

页码: 3015-3034

摘要： Parkinson's disease (PD),known as one of the most universal neurodegenerative diseases,is a ser...
125. Recent developments in the medicinal chemistry of single boron atom-containing compounds

作者： Shu Song Ping Gao Lin Sun Dongwei Kang Jacob Kongsted Vasanthanathan Poongavanam Peng Zhan Xinyong Liu

刊名：药学学报(英文版)

发表期刊： 2021年10期

页码: 3035-3059

摘要： Various boron-containing drugs have been approved for clinical use over the past two de-cades,a...
126. MCDB:A comprehensive curated mitotic catastrophe database for retrieval,protein sequence alignment,and target prediction

作者： Le Zhang Lei Zhang Yue Guo Ming Xiao Lu Feng Chengcan Yang Guan Wang Liang Ouyang

刊名：药学学报(英文版)

发表期刊： 2021年10期

页码: 3092-3104

摘要： Mitotic catastrophe (MC) is a form of programmed cell death induced by mitotic process dis-orde...
127. TRIB3-GSK-3β interaction promotes lung fibrosis and serves as a potential therapeutic target

作者： Shanshan Liu Xiaoxi Lv Xupeng Wei Chang Liu Qiao Li Jiali Min Fang Hua Xiaowei Zhang Ke Li Pingping Li Yang Xiao Zhuowei Hu Bing Cui

刊名：药学学报(英文版)

发表期刊： 2021年10期

页码: 3105-3119

摘要： Pulmonary fibrosis (PF) is a chronic,progressive,fatal interstitial lung disease with limited a...
128. PD0325901,an ERK inhibitor,enhances the efficacy of PD-1 inhibitor in non-small cell lung carcinoma

作者： Min Luo Yuhui Xia Fang Wang Hong Zhang Danting Su Chaoyue Su Chuan Yang Shaocong Wu Sainan An Suxia Lin Liwu Fu

刊名：药学学报(英文版)

发表期刊： 2021年10期

页码: 3120-3133

摘要： ERK pathway regulated the programmed death ligand-1 (PD-L1) expression which was linked to the ...
129. Tubeimoside-1 induces TFEB-dependent lysosomal degradation of PD-L1 and promotes antitumor immunity by targeting mTOR

作者： Xiaojia Liu Mingxiao Yin Jingwen Dong Genxiang Mao Wenjian Min Zean Kuang Peng Yang Lu Liu Na Zhang Hongbin Deng

刊名：药学学报(英文版)

发表期刊： 2021年10期

页码: 3134-3149

摘要： Programmed cell death ligand 1 (PD-L1)/programmed cell death protein 1 (PD-1) cascade is an eff...
130. 3D disorganization and rearrangement of genome provide insights into pathogenesis of NAFLD by integrated Hi-C,Nanopore,and RNA sequencing

作者： Lina Xu Lianhong Yin Yan Qi Xuemei Tan Meng Gao Jinyong Peng

刊名：药学学报(英文版)

发表期刊： 2021年10期

页码: 3150-3164

摘要： The three-dimensional (3D) conformation of chromatin is integral to the precise regulation of g...
131. Salmonella flagella confer anti-tumor immunological effect via activating Flagellin/TLR5 signalling within tumor microenvironment

作者： Jianxiang Chen Yiting Qiao Guo Chen Cunjie Chang Heng Dong Bo Tang Xiawei Cheng Xiufeng Liu Zichun Hua

刊名：药学学报(英文版)

发表期刊： 2021年10期

页码: 3165-3177

摘要： Salmonella.:mediated cancer therapy has achieved remarkable anti-tumor effects in experi-mental...
132. Cholesterol-associated lysosomal disorder triggers cell death of hematological malignancy:Dynamic analysis on cytotoxic effects of LW-218

作者： Po Hu Hui Li Wenzhuo Sun Hongzheng Wang Xiaoxuan Yu Yingjie Qing Zhanyu Wang Mengyuan Zhu Jingyan Xu Qinglong Guo Hui Hui

刊名：药学学报(英文版)

发表期刊： 2021年10期

页码: 3178-3192

摘要： The integrity of lysosomes is of vital importance to survival of tumor ceils.We demonstrated th...
133. Ligand-based substituent-anchoring design of selective receptor-interacting protein kinase 1 necroptosis inhibitors for ulcerative colitis therapy

作者： Jing Zhu Meng Xin Congcong Xu Yuan He Wannian Zhang Zhibin Wang Chunlin Zhuang

刊名：药学学报(英文版)

发表期刊： 2021年10期

页码: 3193-3205

摘要： Receptor-interacting protein (RIP) kinase 1 is involved in immune-mediated inflammatory disease...
134. Discovery of a subtype-selective,covalent inhibitor against palmitoylation pocket of TEAD3

作者： Tian Lu Yong Li Wenchao Lu TWGM Spitters Xueyu Fang Jun Wang Simian Cai Jing Gao Yanting Zhou Zhe Duan Huan Xiong Liping Liu Qi Li Hualiang Jiang Kaixian Chen Hu Zhou Hua Lin Huijin Feng Bing Zhou Christopher L.Antos Cheng Luo

刊名：药学学报(英文版)

发表期刊： 2021年10期

页码: 3206-3219

摘要： The TEA domain (TEAD) family proteins (TEAD1-4) are essential transcription factors that contro...
135. Bioresponsive micro-to-nano albumin-based systems for targeted drug delivery against complex fungal infections

作者： Liting Cheng Miao-Miao Niu Tong Yan Zhongyi Ma Kexin Huang Ling Yang Xin Zhong Chong Li

刊名：药学学报(英文版)

发表期刊： 2021年10期

页码: 3220-3230

摘要： As a typical human pathogenic fungus,Cryptococcus neoformans is a life-threatening inva-sive fu...
136. Self-assembled FeS-based cascade bioreactor with enhanced tumor penetration and synergistic treatments to trigger robust cancer immunotherapy

作者： Hao Ren Jiahui Yong Qingqing Yang Zhen Yang Zhangya Liu Yan Xu Hao Wang Xing Jiang Wenjun Miao Xueming Li

刊名：药学学报(英文版)

发表期刊： 2021年10期

页码: 3244-3261

摘要： Major challenges for cancer treatment are how to effectively eliminate primary tumor and suffic...
137. Cancer-specific calcium nanoregulator suppressing the generation and circulation of circulating tumor cell clusters for enhanced anti-metastasis combinational chemotherapy

作者： Dan Li Yingli Wang Chang Li Qiu Wang Bingjun Sun Haotian Zhang Zhonggui He Jin Sun

刊名：药学学报(英文版)

发表期刊： 2021年10期

页码: 3262-3271

摘要： Tumor metastasis is responsible for chemotherapeutic failure and cancer-related death.More-over...
138. Cytosolic delivery of the immunological adjuvant Poly I:C and cytotoxic drug crystals via a carrier-free strategy significantly amplifies immune response

作者： Xiaoqing Du Yuqi Hou Jia Huang Yan Pang Chenlu Ruan Wei Wu Chenjie Xu Hongwei Zhang Lifang Yin Wei He

刊名：药学学报(英文版)

发表期刊： 2021年10期

页码: 3272-3285

摘要： Co-delivery of chemotherapeutics and immunostimulant or chemoimmunotherapy is an emerging strat...
139. TPGS/hyaluronic acid dual-functionalized PLGA nanoparticles delivered through dissolving microneedles for markedly improved chemo-photothermal combined therapy of superficial tumor

作者： Tingting Peng Yao Huang Xiaoqian Feng Chune Zhu Shi Yin Xinyi Wang Xuequn Bai Xin Pan Chuanbin Wu

刊名：药学学报(英文版)

发表期刊： 2021年10期

页码: 3297-3309

摘要： Nanoparticles (NPs) have shown potential in cancer therapy,while a single administration confer...
140. Functional identification of the terpene synthase family involved in diterpenoid alkaloids biosynthesis in Aconitum carmichaelii

作者： Liuying Mao Baolong Jin Lingli Chen Mei Tian Rui Ma Biwei Yin Haiyan Zhang Juan Guo Jinfu Tang Tong Chen Changjiangsheng Lai Guanghong Cui Luqi Huang

刊名：药学学报(英文版)

发表期刊： 2021年10期

页码: 3310-3321

摘要： Aconitum carmichaelii is a high-value medicinal herb widely used across China,Japan,and other A...
141. Construction of acetyl-CoA and DBAT hybrid metabolic pathway for acetylation of 10-deacetylbaccatin Ⅲ to baccatin Ⅲ

作者： Hao Wang Bo-Yong Zhang Ting Gong Tian-Jiao Chen Jing-Jing Chen Jin-Ling Yang Ping Zhu

刊名：药学学报(英文版)

发表期刊： 2021年10期

页码: 3322-3334

摘要： 10-Deacetylbaccatin Ⅲ (10-DAB) C10 acetylation is an indispensable procedure for Taxol semi-syn...
142. Commentary:PROTACs make undruggable targets druggable:Challenge and opportunity

作者： Bin Lu Jianpin Ye

刊名：药学学报(英文版)

发表期刊： 2021年10期

页码: 3335-3336

摘要： Proteostasis (protein homeostasis) ensures precise adjustment of cellular demand to proteins in...
143. Traditional Chinese medicine in COVID-19

作者： Ming Lyu Guanwei Fan Guangxu Xiao Taiyi Wang Dong Xu Jie Gao Shaoqin Ge Qingling Li Yuling Ma Han Zhang Jigang Wang Yuanlu Cui Junhua Zhang Yan Zhu Boli Zhang

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3337-3363

摘要： COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has spre...
144. Pharmacological insights into autophagy modulation in autoimmune diseases

作者： Ming-Yue Wu Er-Jin Wang Du Feng Min Li Richard D.Ye Jia-Hong Lu

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3364-3378

摘要： As a cellular bulk degradation and survival mechanism,autophagy is implicated in diverse biolog...
145. Advances and challenges in the treatment of esophageal cancer

作者： Shiming He Jian Xu Xiujun Liu Yongsu Zhen

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3379-3392

摘要： Esophageal cancer(EC)is one of the most common cancers with high morbidity and mor-tality rates...
146. Applying artificial intelligence for cancer immunotherapy

作者： Zhijie Xu Xiang Wang Shuangshuang Zeng Xinxin Ren Yuanliang Yan Zhicheng Gong

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3393-3405

摘要： Artificial intelligence(AI)is a general term that refers to the use of a machine to imitate int...
147. Personalized medicine of non-gene-specific chemotherapies for non-small cell lung cancer

作者： Wenxiao Jiang Guiqing Cai Peter Hu Yue Wang

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3406-3416

摘要： Non-small cell lung cancer is recognized as the deadliest cancer across the globe.In some areas...
148. Gains from no real PAINS:Where'Fair Trial Strategy'stands in the development of multi-target ligands

作者： Jianbo Sun Hui Zhong Kun Wang Na Li Li Chen

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3417-3432

摘要： Compounds that selectively modulate multiple targets can provide clinical benefits and are an a...
149. Targeting RAS phosphorylation in cancer therapy:Mechanisms and modulators

作者： Yuran Qiu Yuanhao Wang Zongtao Chai Duan Ni Xinyi Li Jun Pu Jie Chen Jian Zhang Shaoyong Lu Chuan Lv Mingfei Ji

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3433-3446

摘要： RAS,a member of the small GTPase family,functions as a binary switch by shifting between inacti...
150. Nano-bio interfaces effect of two-dimensional nanomaterials and their applications in cancer immunotherapy

作者： Zhongmin Tang Yufen Xiao Na Kong Chuang Liu Wei Chen Xiangang Huang Daiyun Xu Jiang Ouyang Chan Feng Cong Wang Junqing Wang Han Zhang Wei Tao

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3447-3464

摘要： The field of two-dimensional(2D)nanomaterial-based cancer immunotherapy combines research from ...

药学学报(英文版)基本信息

刊名	药学学报(英文版)	主编
曾用名
主办单位		主管单位
出版周期	双月刊	语种	eng
ISSN	2211-3835	CN	10-1171/R
邮编	100050	电子邮箱	yxxb@imm.ac.cn
电话	010-63026192	网址
地址	北京市先农坛街1号