第6页_药学学报(英文版)2021年出版文献-钛学术文献服务平台

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药学学报(英文版)

投稿

Acta Pharmaceutica Sinica B

CSTPCD

影响因子 1.2053

ISSN：

2211-3835

CN：

10-1171/R

出版周期：

双月刊

邮编：

100050

地址：

北京市先农坛街1号

出版文献量（篇）

688

总下载数（次）

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151. Sinomenine ester derivative inhibits glioblastoma by inducing mitochondria-dependent apoptosis and autophagy by PI3K/AKT/mTOR and AMPK/mTOR pathway

作者： Xiangjin Zheng Wan Li Huanli Xu Jinyi Liu Liwen Ren Yihui Yang Sha Li Jinhua Wang Tengfei Ji Guanhua Du

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3465-3480

摘要： Glioblastoma multiforme(GBM)in the central nervous system is the most lethal advanced glioma an...
152. Bruceine D inhibits HIF-1α-mediated glucose metabolism in hepatocellular carcinoma by blocking ICAT/β-catenin interaction

作者： Rui Huang Lijun Zhang Jinmei Jin Yudong Zhou Hongwei Zhang Chao Lv Dong Lu Ye Wu Hong Zhang Sanhong Liu Hongzhuan Chen Xin Luan Weidong Zhang

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3481-3492

摘要： Hepatocellular carcinoma(HCC)is one of the leading causes of cancer-related deaths,char-acteriz...
153. Ginsenoside Rg1 ameliorates blood-brain barrier disruption and traumatic brain injury via attenuating macrophages derived exosomes miR-21 release

作者： Kefeng Zhai Hong Duan Wei Wang Siyu Zhao Ghulam Jilany Khan Mengting Wang Yuhan Zhang Kiran Thakur Xuemei Fang Chao Wu Jianbo Xiao Zhaojun Wei

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3493-3507

摘要： During the traumatic brain injury(TBI),improved expression of circulatory miR-21 serves as a di...
154. Ablation of Akt2 and AMPKα2 rescues high fat diet-induced obesity and hepatic steatosis through Parkin-mediated mitophagy

作者： Shuyi Wang Jun Tao Huaguo Chen Machender R.Kandadi Mingming Sun Haixia Xu Gary D.Lopaschuk Yan Lu Junmeng Zheng Hu Peng Jun Ren

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3508-3526

摘要： Given the opposing effects of Akt and AMP-activated protein kinase(AMPK)on metabolic homeostasi...
155. Integrative lipidomic and transcriptomic study unravels the therapeutic effects of saikosaponins A and D on non-alcoholic fatty liver disease

作者： Xiaojiaoyang Li Junde Ge Yajing Li Yajie Cai Qi Zheng Nana Huang Yiqing Gu Qi Han Yunqian Li Rong Sun Runping Liu

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3527-3541

摘要： Nonalcoholic fatty liver disease(NAFLD)has become one of the most prominent causes of chronic l...
156. Discovery of a potent FKBP38 agonist that ameliorates HFD-induced hyperlipidemia via mTOR/P70S6K/SREBPs pathway

作者： Ping-Ting Xiao Zhi-Shen Xie Yu-Jia Kuang Shi-Yu Liu Chun Zeng Ping Li E-Hu Liu

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3542-3552

摘要： The mammalian target of rapamycin(mTOR)-sterol regulatory element-binding proteins(SREBPs)signa...
157. Protocatechuic aldehyde protects cardiomycoytes against ischemic injury via regulation of nuclear pyruvate kinase M2

作者： Xunxun Wu Lian Liu Qiuling Zheng Haiping Hao Hui Ye Ping Li Hua Yang

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3553-3566

摘要： Rescuing cells from stress damage emerges a potential therapeutic strategy to combat myocardial...
158. Discovery of a small molecule inhibitor of cullin neddylation that triggers ER stress to induce autophagy

作者： Yanan Li Chaorong Wang Tiantian Xu Peichen Pan Qing Yu Lei Xu Xiufang Xiong Tingjun Hou Sunliang Cui Yi Sun

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3567-3584

摘要： Protein neddylation is catalyzed by a three-enzyme cascade,namely an E1 NEDD8-activating enzyme...
159. Integrated in silico formulation design of self-emulsifying drug delivery systems

作者： Haoshi Gao Haoyue Jia Jie Dong Xinggang Yang Haifeng Li Defang Ouyang

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3585-3594

摘要： The drug formulation design of self-emulsifying drug delivery systems(SEDDS)often re-quires num...
160. Self-assembled ternary hybrid nanodrugs for overcoming tumor resistance and metastasis

作者： Xu Cheng Dapeng Li Jiaxi Xu Bing Wei Qin Fang Longshun Yang Yanbing Xue Xin Wang Rupei Tang

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3595-3607

摘要： Traditional chemotherapy exhibits a certain therapeutic effect toward malignant cancer,but easi...
161. A smart O2-generating nanocarrier optimizes drug transportation comprehensively for chemotherapy improving

作者： Xiaojuan Zhang Chuanchuan He Yun Sun Xiaoguang Liu Yan Chen Chen Chen Ruicong Yan Ting Fan Tan Yang Yao Lu Jun Luo Xiang Ma Guangya Xiang

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3608-3621

摘要： Drug transportation is impeded by various barriers in the hypoxic solid tumor,resulting in comp...
162. Genetically-engineered"all-in-one"vaccine platform for cancer immunotherapy

作者： Aihua Wu Yingzhi Chen Hairui Wang Ya Chang Meng Zhang Pengfei Zhao Yisi Tang Qin Xu Zhuangzhi Zhu Yang Cao Yongzhuo Huang

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3622-3635

摘要： An essential step for cancer vaccination is to break the immunosuppression and elicit a tumor-s...
163. Pure photosensitizer-driven nanoassembly with core-matched PEGylation for imaging-guided photodynamic therapy

作者： Shenwu Zhang Yuequan Wang Zhiqiang Kong Xuanbo Zhang Bingjun Sun Han Yu Qin Chen Cong Luo Jin Sun Zhonggui He

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3636-3647

摘要： Pure drug-assembled nanomedicines(PDANs)are currently under intensive investigation as promisin...
164. Tripodalsporormielones A-C,unprecedented cage-like polyketides with complex polyvdent bridged and fused ring systems

作者： Guodong Chen Bingxin Zhao Meijuan Huang Jia Tang Yanbing Li Liangdong Guo Rongrong He Dan Hu Xinsheng Yao Hao Gao

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3648-3654

摘要： A chemical investigation on Sporormiella sp.led to the isolation and structural elucidation of ...
165. Tricarbocyclic core formation of tyrosine-decahydrofluorenes implies a three-enzyme cascade with XenF-mediated sigmatropic rearrangement as a prerequisite

作者： Zhiguo Liu Wei Li Peng Zhang Jie Fan Fangbo Zhang Caixia Wang Shuming Li Yi Sun Shilin Chen Wenbing Yin

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3655-3664

摘要： Tyrosine-decahydrofluorene derivatives feature a fused[6.5.6]tricarbocyclic core and a 13-membe...
166. Spatial-resolved metabolomics reveals tissue-specific metabolic reprogramming in diabetic nephropathy by using mass spectrometry imaging

作者： Zhonghua Wang Wenqing Fu Meiling Huo Bingshu He Yaqi Liu Lu Tian Wanfang Li Zhi Zhou Baili Wang Jianzhen Xia Yanhua Chen Jinfeng Wei Zeper Abliz

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3665-3677

摘要： Detailed knowledge on tissue-specific metabolic reprogramming in diabetic nephropathy(DN)is vit...
167. Preparing anti-SARS-CoV-2 agent EIDD-2801 by a practical and scalable approach,and quick evaluation via machine learning

作者： Zhen Qin Bin Dong Renbing Wang Dechun Huang Jubo Wang Xi Feng Jinlei Bian Zhiyu Li

刊名：药学学报(英文版)

发表期刊： 2021年11期

页码: 3678-3682

摘要： EIDD-2801 is an orally bioavailable prodrug,which will be applied for emergency use autho-rizat...
168. Editorial of Special Column on Drug-and Chemical-Induced Liver Injury

作者： James Luyendyk Dafna Groeneveld

刊名：药学学报(英文版)

发表期刊： 2021年12期

页码: 3683-3684

摘要： We are pleased to present a Special Column on"Drug-and Chemical-induced Liver Injury".The scope...
169. Preclinical models of idiosyncratic drug-induced liver injury(iDILI):Moving towards prediction

作者： Antonio Segovia-Zafra Daniel E.Di Zeo-Sánchez Carlos López-Gómez Zeus Pérez-Valdés Eduardo García-Fuentes Raúl J.Andrade M.Isabel Lucena Marina Villanueva-Paz

刊名：药学学报(英文版)

发表期刊： 2021年12期

页码: 3685-3726

摘要： Idiosyncratic drug-induced liver injury(iDILI)encompasses the unexpected harms that pre-scripti...
170. Mechanisms of immune checkpoint inhibitor-mediated liver injury

作者： Layla Shojaie Myra Ali Andrea Iorga Lily Dara

刊名：药学学报(英文版)

发表期刊： 2021年12期

页码: 3727-3739

摘要： The immune checkpoints,cytotoxic T-lymphocyte-associated antigen 4(CTLA-4)and pro-grammed cell ...
171. Recommendations for the use of the acetaminophen hepatotoxicity model for mechanistic studies and how to avoid common pitfalls

作者： Hartmut Jaeschke Olamide B.Adelusi Jephte Y.Akakpo Nga T.Nguyen Giselle Sanchez-Guerrero David S.Umbaugh Wen-Xing Ding Anup Ramachandran

刊名：药学学报(英文版)

发表期刊： 2021年12期

页码: 3740-3755

摘要： Acetaminophen(APAP)is a widely used analgesic and antipyretic drug,which is safe at ther-apeuti...
172. Environmental toxicant-induced maladaptive mitochondrial changes:A potential unifying mechanism in fatty liver disease?

作者： Regina D.Schnegelberger Anna L.Lang Gavin E.Arteel Juliane I.Beier

刊名：药学学报(英文版)

发表期刊： 2021年12期

页码: 3756-3767

摘要： Occupational and environmental exposures to industrial chemicals are well known to cause hepato...
173. Environmental exposure as a risk-modifying factor in liver diseases:Knowns and unknowns

作者： Juliane I.Beier Gavin E.Arteel

刊名：药学学报(英文版)

发表期刊： 2021年12期

页码: 3768-3778

摘要： Liver diseases are considered to predominantly possess an inherited or xenobiotic etiology.Howe...
174. Mechanistic studies of PEG-asparaginase-induced liver injury and hepatic steatosis in mice

作者： Gundala Venkata Naveen Kumar Keito Hoshitsuki Sanjay Rathod Manda J.Ramsey Lauren Kokai Erin E.Kershaw Wen Xie Christian A.Fernandez

刊名：药学学报(英文版)

发表期刊： 2021年12期

页码: 3779-3790

摘要： PEGylated-L-asparaginase(PEG-ASNase)is a chemotherapeutic agent used to treat pediatric acute l...
175. Dual roles of p62/SQSTM1 in the injury and recovery phases of acetaminophen-induced liver injury in mice

作者： Hui Qian Qingyun Bai Xiao Yang Jephte Y.Akakpo Lili Ji Li Yang Thomas Rülicke Kurt Zatloukal Hartmut Jaeschke Hong-Min Ni Wen-Xing Ding

刊名：药学学报(英文版)

发表期刊： 2021年12期

页码: 3791-3805

摘要： Acetaminophen(APAP)overdose can induce liver injury and is the most frequent cause of acute liv...
176. Proteomics and metabolic phenotyping define principal roles for the aryl hydrocarbon receptor in mouse liver

作者： Jian Jin Banrida Wahlang Monika Thapa Kimberly Z.Head Josiah E.Hardesty Sudhir Srivastava Michael L.Merchant Shesh N.Rai Russell A.Prough Matthew C.Cave

刊名：药学学报(英文版)

发表期刊： 2021年12期

页码: 3806-3819

摘要： Dioxin-like molecules have been associated with endocrine disruption and liver disease.To bette...
177. The key role of gut-liver axis in pyrrolizidine alkaloid-induced hepatotoxicity and enterotoxicity

作者： Yisheng He Jiang Ma Xiaoyu Fan Liang Ding Xinxin Ding Qing-Yu Zhang Ge Lin

刊名：药学学报(英文版)

发表期刊： 2021年12期

页码: 3820-3835

摘要： Pyrrolizidine alkaloids(PAs)are the most common phytotoxins with documented human hepatotoxicit...
178. Exogenous phosphatidic acid reduces acetaminophen-induced liver injury in mice by activating hepatic interleukin-6 signaling through inter-organ crosstalk

作者： Melissa M.Clemens Stefanie Kennon-McGill Joel H.Vazquez Owen W.Stephens Erich A.Peterson Donald J.Johann Felicia D.Allard Eric U.Yee Sandra S.McCullough Laura P.James Brian N.Finck Mitchell R.McGill

刊名：药学学报(英文版)

发表期刊： 2021年12期

页码: 3836-3846

摘要： We previously demonstrated that endogenous phosphatidic acid(PA)promotes liver regener-ation af...
179. Bile acid homeostasis in female mice deficient in Cyp7a1 and Cyp27a1

作者： Daniel Rizzolo Bo Kong Rulaiha E.Taylor Anita Brinker Michael Goedken Brian Buckley Grace L.Guo

刊名：药学学报(英文版)

发表期刊： 2021年12期

页码: 3847-3856

摘要： Bile acids(BAs)are amphipathic molecules important for metabolism of cholesterol,absorp-tion of...
180. Hepatotoxicity reports in the FDA adverse event reporting system database:A comparison of drugs that cause injury via mitochondrial or other mechanisms

作者： Payal Rana Michael D.Aleo Xuerong Wen Stephen Kogut

刊名：药学学报(英文版)

发表期刊： 2021年12期

页码: 3857-3868

摘要： Drug-induced liver injury(DILI)is a leading reason for preclinical safety attrition and post-ma...

药学学报(英文版)基本信息

刊名	药学学报(英文版)	主编
曾用名
主办单位		主管单位
出版周期	双月刊	语种	eng
ISSN	2211-3835	CN	10-1171/R
邮编	100050	电子邮箱	yxxb@imm.ac.cn
电话	010-63026192	网址
地址	北京市先农坛街1号