【正】Metabonomics has been applied successfully in different research fields such as toxicology and pharmacology(1-7).However,application of metabonomics in nutritional research is still at infancy stage of development.Historically outcome measurement as an analytical approach has been widely used in nutritional research.This approach provides direct evidence linking the effect of nutrient intake on heath and disease.However,outcome measurement does not elucidate the underlying mechanistic effect of a nutrient intake