Generation of fertile sperm in a culture dish: clinical implications

• 来源期刊: 亚洲男性学杂志（英文版）
• 年，卷（期）: 2011,（4）
• 页码范围: 618-619
• 页数: 2页
• 语种: 英文
• DOI: 10.1038/aja.2011.52

摘要

Spermatogenesis is a tightly regulated process of development for the generation of mature spermatozoa.Mammalian spermatogenesis occurs in the convoluted seminiferous tubules of the testes, where spermatogenic stem cells (SSCs) reside on sustentacular Sertoli cells of somatic origin, forming a germinal epithelial structure.Spermato genesis is accomplished in a complicated,timely controlled differentiation of SSCs into premeiotic primary spermatocytes, followed by formation of postmeiotic round spermatids and their subsequent maturation into spermatozoa.