Osteonecrosis: The perils of steroids. A review of the literature and case report

• 作者: Ben J. Brooker Prue P. A. Keith
• 来源期刊: 临床医学病理报告(英文)
• 学科: 医学
• 关键词: OSTEONECROSIS CORTICOSTEROIDS STEROIDS AVASCULAR NECROSIS of Bone
• 年，卷（期）: 2012,（2）
• 页码范围: 26-37
• 页数: 12页
• 分类号: R5

摘要

Non-traumatic osteonecrosis is a cause of joint pain and deformity, not uncommonly caused by corticosteroid use. Despite this, corticosteroid induced osteonecrosis is poorly represented in the literature. We performed a detailed review of corticosteroid induced osteonecrosis, including aetiology, prevention, screening, clinical presentation, investigations, staging systems and treatment. We present this in the context of a patient at our institution who developed bilateral hip, shoulder and knee osteonecrosis following high dose corticosteroid therapy for dermatomyositis.