Morbid Obesity in Diabetes Mellitus Type 2 and Exenatide

• 作者: Alfonso López Ruiz Alicia Hernández Torres Ana Belén Hernández Cascales María Angeles Iba?ez Gil María Dolores Hellín Gil Pedro Pujante Alarcon
• 来源期刊: 药理与制药(英文)
• 学科: 医学
• 关键词: TYPE 2 DIABETES and OBESITY EXENATIDE
• 年，卷（期）: 2014,（2）
• 页码范围: 149-152
• 页数: 4页
• 分类号: R5

摘要

Worldwide, the prevalence of diabetes and obesity is increasing in recent years in developed countries. The first step of treatment is changes in lifestyle and in case of failure to initiate drug treatment. In our case, the patient with morbid obesity and glucose intolerance to metformin therapy was initiated without achieving weight loss and loss of glycemic control after 6 months of treatment. It was decided to add exenatide as an alternative to bariatric surgery. At the end of the study (12 months), it showed a weight reduction of 20.8% (Table 1), 20.83% BMI, glycosylated hemoglobin decrease of 2 points, and improved the lipid profile. So exenatide may be an acceptable option in the use of patient profile. It would be necessary to seek a new alternative treatment with minimal side effects and less healthcare costs.