Objective: To describe a rare case of angiosarcoma thyroid in Indian subcontinent with its successful management. Case report: A 60-year-old male with swelling in neck for 20years with sudden increase in the size during last 3 months. Fine needle aspiration cytology suggested anaplastic carcinoma. The patient underwent total thyroidectomy with central and lateral neck dissection. On histopathology, the diagnosis of angiosarcoma was suspected. Immunohisto chemistry confirmed the diagnosis of angiosarcoma. Post-operative chemoradiation was given with no recurrence at 10 months of follow up. Conclusion: Though rare, angiosarcoma should be included as differential diagnosis in cases of long standing goiters with recent rapid increase in size. Immunohistochemistry is crucial for diagnosis and should be considered in these patients. Early and prompt diagnosis will help in providing curative treatment in such patients.