0Adipose-derived stem cells: Implications in tissue regeneration

• 作者: Wakako Tsuji J Peter Rubin Kacey G Marra
• 来源期刊: 世界干细胞杂志：英文版（电子版）
• 学科: 医学
• 关键词: MESENCHYMAL STEM CELLS Adipose-derived STEM CELLS DIFFERENTIATION Growth factors TISSUE engi-neering Clinical trials
• 年，卷（期）: 2014,（3）
• 页码范围: 312-321
• 页数: 10页
• 分类号: R329

摘要

Adipose-derived stem cells(ASCs) are mesenchymal stem cells(MSCs) that are obtained from abundant adipose tissue, adherent on plastic culture flasks, can be expanded in vitro, and have the capacity to differ-entiate into multiple cell lineages. Unlike bone marrow-derived MSCs, ASCs can be obtained from abundant adipose tissue by a minimally invasive procedure, which results in a high number of cells. Therefore, ASCs are promising for regenerating tissues and organs dam-aged by injury and diseases. This article reviews the implications of ASCs in tissue regeneration.