Peroral endoscopic myotomy： Time to change our opinionregarding the treatment of achalasia？

• 作者: Marcel Tantau Dana Crisan
• 来源期刊: 世界胃肠内镜杂志：英文版（电子版）
• 学科: 医学
• 关键词: Peroral ENDOSCOPIC MYOTOMY ACHALASIA MYOTOMY ENDOSCOPIC TREATMENT
• 年，卷（期）: 2015,（3）
• 页码范围: 237-246
• 页数: 10页
• 分类号: R

摘要

Peroral endoscopic myotomy （POEM） is a new endoscopictreatment for achalasia. Compared to the classicalsurgical myotomy, POEM brings at least the advantageof minimal invasiveness. The data provided until nowsuggest that POEM offers excellent short-term symptomresolution, with improvement of dysphagia in more than90% of treated patients, with encouraging manometricoutcomes and low incidence of postprocedural gastroesophagealreflux. The effectiveness of this noveltherapy requires long-term follow-up and comparativestudies with other treatment modalities for achalasia.This technique requires experts in interventionalendoscopy, with a learning curve requiring more than 20cases, including training on animal and cadaver models,and with a need for structured proctoring during thefirst cases. This review aims to summarize the data onthe technique, outcomes, safety and learning curve ofthis new endoscopic treatment of achalasia.