A Voice Coil Powered Controllable Micro-Jet Injection System

• 作者: Kai Chen Laiwu Miao Zhigang Feng
• 来源期刊: 生物医学工程(英文)
• 学科: 医学
• 关键词: JET INJECTION Micro-Jet Trans-Dermal DRUG Delivery
• 年，卷（期）: 2015,（9）
• 页码范围: 632-642
• 页数: 11页
• 分类号: R73

摘要

A medical device of micro-jet injection for drug delivery is described in this paper. The device is powered by a Lorentz force driver (or voice coil motor, VCM) and is able to perform pulsed injection through controlling the direction of the current passing through the device. The driving force and the resulting injection pressure are also controllable through control of the current intensity of the VCM. A physical model was established by combining the existing jet injection model with the relationship of the driving force obtained from a finite-element-method (FEM) analysis, and was verified by experimental measurements. The numerical calculation of the physical model reveals the relationship between the injection pressure and the current intensity of VCM under system conditions. In normal cases, the injection dose can be varied. Thus the relationship between the current intensity of VCM and the dose value was numerically obtained under the condition for the maximum injection pressure to be above a threshold value. These results can be used for optimization of the device.