3-70 Down Regulation of Nrf2 Promotes Apoptosis through Nrf2 Mediated Notch Signaling in Non-small Cell Lung Cancer Cells

• 作者: Zhang Hong Zhao Qiuyue
• 来源期刊: 中国科学院近代物理研究所和兰州重离子研究装置年报：英文版
• 学科: 物理学
• 关键词: MEDIATED NOTCH SIGNALING
• 年，卷（期）: 2015,（1）
• 页码范围: 174-174
• 页数: 1页
• 分类号: O4

摘要

The nuclear factor erythroid-2-related factor 2 (Nrf2) is a crucial regulator of the cellular antioxidant system. Nrf2 is often constitutively activated in non-small-cell lung cancer (NSCLC) cell lines, which promotes cytoprotection against oxidative stress and xenobiotics[1??3].