Prognostic scoring systems for clinical course and survival in idiopathic pulmonary fibrosis

• 作者: Ermanno Puxeddu Paola Rogliani
• 来源期刊: 世界呼吸病学杂志
• 学科: 医学
• 关键词: IDIOPATHIC PULMONARY FIBROSIS Prognosis SURVIVAL SCORING systems
• 年，卷（期）: 2016,（1）
• 页码范围: 14-23
• 页数: 10页
• 分类号: R

摘要

Idiopathic pulmonary fibrosis(IPF)is the most common and rapidly fatal among idiopathic interstitial pneumonias.Its clinical course is variable.A significant fraction of the population of patients display a slow disease course and can remain stable for years,while other patients show a rapid progressive course and may die within few months from diagnosis.For these reasons estimating prognosis of IPF patients is extremely difficult and has important clinical repercussions on optimal patients management including patients referral for lung transplantation.Several studies have tried to address this key point in the course of the two last decades analyzing different clinical,functional,radiological and biological variables.The purpose of this review is to assess relevant studies published on this subject and to examine the variety of prognostic predictors proposed along with staging systems.