Infrared autofluorescence, short-wave autofluorescence and spectral-domain optical coherence tomography of optic disk melanocytomas

• 作者: Dong-Jie Sun Hai-Yan Wang Peng Zhang Wen-Qin Xu Yan-Nian Hui Yu-Sheng Wang Zi-Feng Zhang
• 来源期刊: 国际眼科杂志：英文版
• 学科: 医学
• 关键词: MELANOCYTOMA ANGIOGRAPHY AUTOFLUORESCENCE optical coherence tomography
• 年，卷（期）: 2016,（5）
• 页码范围: 713-716
• 页数: 4页
• 分类号: R77

摘要

AIM: To investigate the findings of infrared fundus autofluorescence(IR-AF) and spectral-domain optical coherence tomography(SD-OCT) in eyes with optic disc melanocytoma(ODM).· METHODS: IR-AF findings and those of other ophthalmologic imaging examinations, including short-wave autofluorescence(SW-AF), fluorescein angiography(FA), fundus color photography, and SD-OCT of 8 eyes of 8 consecutive cases with ODM were assessed.·RESULTS: The ODMs in all cases(100%) presented similar IR-AF, SW-AF, and FA findings. On IR-AF images, ODMs showed outstanding hyper-AF with well-defined outline. On SW-AF images, the area of ODMs presented as hypo-AF. FA images revealed the leaking retinal telangiectasia on the surface of the ODMs. On SDOCT images in 8 cases(100%), the ODMs were sloped with highly reflective surface, which were disorganized retina and optic nerve layers. In 7 cases(87.5%), peripapillary choroids were involved. The melanocytomas of 8 cases(100%) presented as optically empty spaces. Vitreous seeds were found in one case(12.5%).· CONCLUSION: IR-AF imaging may provide a new modality to evaluate the pathologic features of ODMs,and together with SW-AF imaging, offers a new tool to study biological characteristics associated with ODMs.SD-OCT is a valuable tool in delimitating the tumor extension and providing morphological information about the adjacent retinal tissue.