Efficacy, safety, predictability, aberrations and corneal biomechnical parameters after SMILE and FLEx： Metaanalysis

• 作者: Jing Ma Li-Kun Xia Nan-Jue Cao
• 来源期刊: 国际眼科杂志：英文版
• 学科: 医学
• 关键词: visual quality ABERRATIONS corneal biomechnical parameters small-incision lenticule extraction femtosecond lenticule extraction
• 年，卷（期）: 2016,（5）
• 页码范围: 757-762
• 页数: 6页
• 分类号: R77

摘要

AIM: To identify possible differences of efficacy, safety predictability, higher-order aberrations and cornea biomechnical parameters after small-incision lenticule extraction(SMILE) and femtosecond lenticule extraction(FLEx).· METHODS: A systematic literature retrieval was conducted in Medline,Embase and the Cochrane Library up to October, 2015. The included studies were subject to a Meta-analysis. Comparison between SMILE and FLEx was measured as pooled odds ratio(OR) or weighted mean differences(WMD). Of 95% confidence intervals(CI) were used to analyze data.·RESULTS: A total of seven studies were included Firstly, there were no differences in uncorrected distance visual acuity(UDVA) 20/20 or better(OR, 1.37; 95% CI0.69 to 2.69; P =0.37) and log MAR UDVA(WMD,-0.02;95% CI,-0.05 to 0.01; P =0.17) after SMILE versus FLEx We found no differences in corrected distance visua acuity(CDVA) unchanged(OR, 0.98; 95% CI, 0.46 to 2.11;P =0.97) and log MAR CDVA(WMD,-0.00; 95% CI,-0.01 to 0.01; P =0.90) either. Secondly, we found no differences in refraction within ±1.00 D(OR, 0.98; 95% CI0.13 to 7.28; P =0.99) and ±0.50 D(OR, 1.62; 95% CI0.62 to 4.28; P =0.33) of target postoperatively. Thirdly for higher-order aberrations, we found no differences in the total higher-order aberrations(WMD,-0.04; 95%CI,-0.09 to 0.01;P =0.14), coma(WMD,-0.04; 95% CI,-0.09 to 0.01; P =0.11), spherical(WMD, 0.01; 95% CI,-0.02 to0.03; P =0.60) and trefoil(WMD,-0.00; 95% CI,-0.04 to0.03; P =0.76). Furthermore, for corneal biomechanica parameters, we also found no differences(WMD, 0.08;95% CI,-0.17 to 0.33; P =0.54) after SMILE versus FLEx.·CONCLUSION: There are no statistically differences in efficacy, safety, predictability, higher-order aberrations and corneal biomechnical parameters postoperative between SMILE and FLEx.