Preliminary Monte Carlo Investigation of Using Ir-192 as the Source for Real Time Imaging Purpose

• 作者: Brian Wang Chengyu Shi
• 来源期刊: 医学物理学、临床工程、放射肿瘤学(英文)
• 学科: 医学
• 关键词: MONTE Carlo Ir-192 HDR Imaging
• 年，卷（期）: 2017,（1）
• 页码范围: 21-30
• 页数: 10页
• 分类号: R73

摘要

The purpose of this study is to investigate the potential use of Ir-192 as the source for real time imaging during HDR (High Dose Rate) brachytherapy treatment. Phantom measurement was performed to determine outside of the body dose. Monte Carlo code, EGSnrcMP egs_inprz, was used for the simulation to calculate the outside of the body x-ray signal for CT reconstruction. Matlab code was developed to reconstruct the Ir-192 source and for 3D visualization in order to assess reconstructed CT resolution, signal-to-noise ratio, and imaging dose information. The measured dose was 0.67 ± 0.04 cGy, which was comparable to the Monte Carlo simulation result 0.71 ± 0.20 cGy. The reconstructed source diameter dimension was 1.3 mm compared with 1.1 mm for the real source dimension. The signal-to-noise ratio was 19.91 db following de-noising. Source position was within a 1 mm difference between programmed and simulated results. Although the Ir-192 signal is weak for CT imaging, it is possible to use it as a CT imaging x-ray source for HDR treatment localization, verification and dosimetry purposes. Further study is needed for the detailed design of an outside of the body CT-like device for use in brachytherapy imaging.