Spontaneous Heparin-Induced Thrombocytopenia Following Orthopaedic Surgery: Case Report and Review of the Literature

• 作者: Caroline Berube Derek F. Amanatullah Malcolm R. DeBaun Michael A. Spinner Michael D. Genualdi
• 来源期刊: 矫形学期刊(英文)
• 学科: 医学
• 关键词: SPONTANEOUS HEPARIN Induced THROMBOCYTOPENIA HIT ARTHROPLASTY Total KNEE ARTHROPLASTY TKA
• 年，卷（期）: 2017,（12）
• 页码范围: 400-407
• 页数: 8页
• 分类号: R5

摘要

Background: Spontaneous heparin induced thrombocytopenia (HIT) is a medical phenomenon whereby patients develop clinical and laboratory features of HIT without prior exposure to heparin. Aim: We present a patient who underwent bilateral total knee replacement complicated by spontaneous HIT causing bilateral adrenal hemorrhage and deep vein thrombosis. Our patient had no prior history of heparin exposure. We reconcile our patient’s presentation with other case reports of spontaneous HIT in patients who had orthopaedic surgery. Conclusion: Spontaneous HIT is a rare but potentially devastating complication associated with total knee arthroplasty.