AIM To analyze neuromuscular activity patterns of the trunk in healthy controls(H)and back pain patients(BPP)during one-handed lifting of light to heavy loads.METHODS After assessment of back pain(graded chronic pain scale according to von Korff)all subjects(n=43)performed a warm-up(treadmill walking).Next,subjects were instructed to lift 3×a 20 kg weight placed in front of them(with both hand)onto a table(height:0.75 m).Subsequently,all subjects lifted with one hand(left-side,3 repetitions)a weight of 1 kg(light),10 kg(middle)and 20 kg(heavy)in random order from the ground up onto the table left of them.Trunk muscle activity was assessed with a 12-lead EMG(6 ventral/6 dorsal muscles;4000 Hz).EMG-RMS(%)was averaged over the 3 repetitions and analyzed for the whole one-handed lifting cycle,then normalized to RMS of the two-handed lifting.Additionally,the mean(normalized)EMG-RMS of four trunk areas[right/left ventral area(VR/VL);right/left dorsal area(DR/DL)]was calculated.Data were analyzed descriptively(mean±SD)followed by student’s t-test comparing H and BPP(α=0.05).With respect to the unequal distribution of subjects in H and BPP,a matched-group analysis was conducted.Seven healthy controls were gender-and age-matched(group Hmatched)to the 7 BPP.In addition,task failure was calculated and compared between H/Hmatched vs BPP usingχ2.RESULTS Seven subjects(3m/4f;32±7 years;171±7 cm;65±11 kg)were assigned to BPP(pain grade≥2)and 36(13m/23f;28±8 years;174±10 cm;71±12 kg)to H(pain grade≤1).H and BPP did not differ significantly in anthropometrics(P>0.05).All subjects were able to lift the light and middle loads,but 57%of BPP and 22%of H were not able to lift the heavy load(all women).χ2 analysis revealed statistically significant differences in task failure between H vs BPP(P=0.03).EMG-RMS ranged from 33%±10%/30%±9%(DL,1 kg)to 356%±148%/283%±80%(VR,20 kg)in H/BPP with no statistical difference between groups regardless of load(P>0.05).However,the EMG-RMS of the VR was greatest in all lifting task