Latest Advances in the Treatment of Post-stroke Limb Spasm with Botulinum Neurotoxin

• 作者: Lingjing Jin Shuhua Chen
• 来源期刊: 医学科学进展杂志(英文)
• 学科: 医学
• 关键词: BOTULINUM NEUROTOXIN POST-STROKE LIMB SPASM GUIDING technology Combination therapy Efficacy evaluation
• 年，卷（期）: 2018,（4）
• 页码范围: 133-139
• 页数: 7页
• 分类号: R

摘要

Objective: To describe the latest progress in the use of botulinum neurotoxin for post-stroke limb spasm. Methods: This paper looks up the relevant research literatures in recent years in PubMed, Web of Science, Springer, Ovid, CNKI, WanFang databases and summarizes them. Results: The latest progress in the use of botulinum neurotoxin for post-stroke limb spasm was studied from the following aspects: the action mechanism of botulinum neurotoxin;efficacy evaluation;injection dose;target muscle selection;guiding technology;combination therapy. Conclusion: Botulinum neurotoxin is the first-line treatment for post-stroke limb spasm. We need to make continuous improvement and progress from the treatment period, injection dose, target muscle selection, guiding technology and efficacy evaluation to improve the quality of life of the majority of post-stroke survivors in China.