Supersaturated Calcium Phosphate Rinse vs. Standard of Care for Mitigating Mucositis in Head and Neck Chemoradiation

• 作者: Brian Pikkula Chris Morris Justin Brock Kathleen Hotze
• 来源期刊: 癌症治疗(英文)
• 学科: 医学
• 关键词: ORAL MUCOSITIS Health CARE COST WHO OM Scale
• 年，卷（期）: 2018,（3）
• 页码范围: 262-267
• 页数: 6页
• 分类号: R73

摘要

Introduction: Oral mucositis (OM) can have a significant impact on patients’ quality of life, pain and treatment costs. Almost all patients receiving head and neck chemoradiation develop OM. Patients and Methods: Twenty patients were evaluated retrospectively for OM when undergoing head and neck chemoradiation. The control, soda/salt rinse, was compared to a powdered supersaturated calcium phosphate rinse (SSCPR), SalivaMAX. Results: The SSCPR group experienced a delay in the onset of OM, which was not statistically significant, and a marked reduction in peak OM that was statistically significant (p > 0.001). Conclusion: This retrospective study demonstrates that a powdered SSCPR is a safe and effective method of oral mucositis mitigation.