Descriptive Epidemiology of Multidrug Resistance Tuberculosis (MDR-TB) in Bangladesh

• 作者: Abu Bakar Siddik Arman Hossain Basana Marma Gias Uddin Ahsan Mohammad Delwer Hossain Hawlader Mohammad Rashed Uzzaman Muhammad Maqsud Hossain Sanjana Zaman
• 来源期刊: 结核病研究(英文)
• 学科: 医学
• 关键词: MDR-TB Risk Factors DESCRIPTIVE Study EPIDEMIOLOGY BANGLADESH
• 年，卷（期）: jhbyjyw_2018,（4）
• 页码范围: 292-301
• 页数: 10页
• 分类号: R73

摘要

Background: The number of reported MDR-TB cases has been increasing in recent years. Objectives: To describe the epidemiological profile of MDR-TB cases in Bangladesh. Design: This was a descriptive cross-sectional study. Settings: The study was conducted among the multi drug resistant tuberculosis patient admitted in the National Institute of Diseases of the Chest and Hospital (NIDCH) Dhaka, Bangladesh. Samples: 148 confirmed cases of MDR-TB. Materials and Methods: Hospital admitted MRD-TB cases were randomly chosen from the above mentioned hospital. Semi-structured and pretested questionnaire were introduced by researcher. Clinical and treatment data i.e. duration of TB drug intake, report of sputum, X-ray and blood test etc. were extracted from the hospital record. Results: Study found, majority of the participants (56.1%) were in the age group of 16 - 30 years. 64.2% of the study subjects were married. Majority of the participants education were whether under primary or primary level. 24.3% participant’s family member and 14.5% of neighbor were having TB. Most common comorbidity were diabetes, pulmonary infection, hearing loss, psychiatric symptoms, chest pain, joint pain etc. 63.5% respondent had high degree of AFB for sputum positivity and more than 98% had positive finding in X-ray chest. On an average ESR was low and also few cases of extremely low ESR were found. 71.6% were under twenty four months regimen. Conclusion: We can conclude that, many possible factors for MDR-TB. There is an urgent need for further study to confirm the exact factors in Bangladesh and address those immediately.