Anal Cancer in a HIV Sero-Positive Bisexual Bachelor—A Case Report and Literature Review

• 作者: J. A. Ashindoitiang M. E. Asuquo S. O. Akpan Victor Nwagbara
• 来源期刊: 临床医学病理报告(英文)
• 学科: 医学
• 关键词: ANAL Cancer Bisexual Human Immune-Deficiency Virus Sero-Positive Status SQUAMOUS Cell Carcinoma
• 年，卷（期）: 2018,（12）
• 页码范围: 601-607
• 页数: 7页
• 分类号: R73

摘要

Anal cancer, especially squamous cell carcinoma (SCC) variety, is evolving with rising incidence globally. This is due to the increasing adoption of risky life styles and social habits even in populations with rare occurrences previously. This case report aims to expose risk factors exhibited by a patient recently managed for anal cancer in our facility before his demise. Early exposure to bisexual orientation, receptive anal intercourse and multiple sexual partners, are notable high risk factors for the development of anal SCC. The permissive role of smoking, illicit drug and alcohol use enhances the disease occurrence. Acquisition of human immune-deficiency virus (HIV) sero-positive status further reduces the body’s immune competence and enhances early age of onset as well as accelerates development of anal SCC. Proper history exploring the risk factors, physical/anorectal examination and histological analysis, are vital for proper diagnosis and staging which guides appropriate treatment with chemo-radiation as mainstay.