Epidemiology and Antibiotic Susceptibility Profile of Methicillin Sensitive Staphylococcus aureus among Livestock and Pet Animals

• 作者: Amjad Islam Aqib Iqra Gulzar Iqra Muzammil Muhammad Aamir Naseer Muhammad Shoaib Zeeshan Ahmad Bhutta
• 来源期刊: 兽医科学研究(英文)
• 学科: 医学
• 关键词: S.aureus MSSA PET Bovine CAPRINE Antibiotic susceptibility
• 年，卷（期）: 2020,（1）
• 页码范围: 16-23
• 页数: 8页
• 分类号: R44

摘要

Staphylococcus aureus is an important zoonotic pathogen that is responsible for a variety of infectious diseases in humans and animals.The present study was designed to check the prevalence and antimicrobial resistance of MSSA from three different animal origins(bovine,caprine and pet).A total of n=450 samples(150 each source)were collected from bovine,caprine and pets.Collected samples were subjected to S.aureus identification by microbiological examination and confirmed S.aureus isolates were put to oxacillin disk diffusion test to declare them MSSA.The MSSA confirmed isolates were subjected to various antibiotics for susceptibility profiling using Kirby Bauer Disk Diffusion test.The present study found higher prevalence of MSSA from caprine origin(goat 83.33%)as compared to pet(cat 69.33%;dog 65.33%)and bovine origin(buffalo 26.66%;cattle 31.66%).The in-vitro findings of current study revealed oxytetracycline and gentamicin presented 100%efficacy against MSSA of all origins while the vancomycin presented>35%,>40%and>65%resistance against MSSA isolated from bovine,caprine and pet origin respectively.However,ciprofloxacin was equally effective(50%)against MSSA from buffalo and cattle while>80%efficacy was noted against MSSA from cat and dogs.Linezolid and amoxicillin+clavulanic acid were 77.78%and 66.67%sensitive to MSSA isolates from caprine milk.The present study found higher prevalence of MSSA from bovine,caprine and pet isolates with diversified pattern of susceptibility of different antibiotics from all sources.