Research status of E3 ubiquitin ligase Smurf2 and related signaling pathways in glioma

• 作者: Qianxu Jin Zongmao Zhao
• 来源期刊: 转化神经科学电子杂志（英文）
• 年，卷（期）: 2020,（2）
• 所属期刊栏目: Review
• 页码范围: 1-8
• 页数: 8页
• 语种: 英文
• DOI: 10.3868/j.issn.2096-0689.2020.02.001

摘要

Glioma is the tumor with the highest incidence in the brain, and it is eager to seek new and effective treatment. The interaction of ubiquitination and deubiquitination regulates many cell activities in organ-isms, and participates in tumor occurrence, development, migration, invasion and other processes. This article sum-marized the progress of E3 ubiquitination ligase smad ubiquitination regulatory factor 2 (Smurf2) and glio-ma-related signaling pathways to assist clinical diagnosis and treatment of glioma.