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摘要:
Degenerative disc disease is the most common cause of low back pain. Intervertebral disc abnormalities are commonly evaluated by magnetic resonance imaging (MRI), and Pfirrmann’s system involves the use of T2-weighted images (T2WI) to classify disc degeneration. However, as this classification is based on visual evaluation, it is not possible to quantify degeneration using this method. The present study was performed to establish an MRI-based intervertebral disc classification system using diffusional kurtosis imaging (DKI), to quantify intervertebral disc water content according to the Pfirrmann classification. Sagittal mean diffusional kurtosis (MK) mapping was performed for the L3/4, L4/5, and L5/S1 intervertebral discs in 32 patients (15 female, 17 male;age range, 24 - 82 years;mean age, 57.7 years). The degree of disc degeneration was assessed in the midsagittal section on T2WI according to the Pfirrmann classification (grade I - V). The relationships between MK values, which are correlated with intervertebral disc composition changes, and grade of degeneration determined using the Pfirrmann classification were analyzed. The MK values tended to decrease with increasing grade of degeneration, and differed significantly between grades I and IV, but not between grade IV and V (P < 0.05, Mann-Whitney U test). DKI is an effective means of detecting the early stages of disc degeneration. Therefore, DKI may be a useful diagnostic tool for quantitative assessment of intervertebral disc degeneration.
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篇名 Classification of Intervertebral Disc Degeneration in Low Back Pain Using Diffusional Kurtosis Imaging
来源期刊 放射学期刊(英文) 学科 医学
关键词 Diffusional Kurtosis Imaging Pfirrmann Classification Mean Diffusional Kurtosis Intervertebral Disc Degeneration Low Back Pain
年,卷(期) 2020,(2) 所属期刊栏目
研究方向 页码范围 79-89
页数 11页 分类号 R73
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Diffusional
Kurtosis
Imaging
Pfirrmann
Classification
Mean
Diffusional
Kurtosis
Intervertebral
Disc
Degeneration
Low
Back
Pain
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研究分支
研究去脉
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相关学者/机构
期刊影响力
放射学期刊(英文)
季刊
2164-3024
武汉市江夏区汤逊湖北路38号光谷总部空间
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256
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