Safety of Transcranial Direct Current Electrical Stimulation in Dermatomyositis: A Case Report

• 作者: Abrah?o Fontes Baptista Clarice Tanaka Julia Maria D’Andréa Greve Lucas de Macedo dos Santos Luiz Felipe Adsuara de Sousa Rafael Giovani Missé Samuel Katsuyuki Shinjo
• 来源期刊: 风湿病与自身免疫疾病期刊(英文)
• 学科: 交通运输
• 关键词: DERMATOMYOSITIS NEUROMODULATION SAFETY Systemic AUTOIMMUNE MYOPATHIES
• 年，卷（期）: 2020,（2）
• 页码范围: 88-93
• 页数: 6页
• 分类号: U28

摘要

Transcranial direct current stimulation (tDCS) has emerged as a nonpharmacological tool in physical rehabilitation. There have currently no studies that evaluated the safety and efficacy of tDCS in patients with dermatomyositis. Case-report: Three adult women with dermatomyositis were allocated randomly to intervention (i-tDCS, one patient) or not (sham-tDCS, two patients) of three consecutive days of tDCS and evaluated in four periods: before-tDCS (PRE), 15 minutes after-tDCS (0th POST), 15 days after-tDCS (15th POST), and 30 days after-tDCS (30th POST). The tDCS was safe throughout the protocol, without disease relapsing or adverse effects related to tDCS. Furthermore, the tDCS increased the muscle torque and total work of dominant and non-dominant elbow flexors in the patient with i-tDCS, when compared to two patients with sham-tDCS. Conclusions: The tDCS was safe and appeared to influence long-term strength in the limb of the patient with stable dermatomyo-sitis.