基本信息来源于合作网站,原文需代理用户跳转至来源网站获取       
摘要:
<b>Background: </b>Non-alcoholic fatty liver disease (NAFLD) has emerged a major challenge and become the leading indication for liver transplantation. We aimed to assess the applicability and performance of real-time elastography (RTE) in diagnosis of liver fibrosis in patients with NAFLD compared with NAFLD fibrosis score (NFS) and FIB-4 index. <b>Patients and Methods:</b> A prospective case-control study was conducted on 260 subjects attended Hepatology, Gastroenterology and Infectious diseases and Internal Medicine departments in Benha University Hospital from Marsh 20, 2018, to September 1, 2019 and divided into group I included 200 cases with NAFLD and group II included 60 healthy control subjects. <b>Results</b>:<b> </b>There was statistically significant increase in FIB-4 scores between two groups (1.39 ± 1.02 and -0.75 ± 0.32 respectively with p < 0.001), also there was statistically significant increase in NAFLD fibrosis score mean ± SD between two groups (-1.74 ± 1.17 and -2.75 ± 0.91 respectively with p < 0.001). Fibrosis stages in NAFLD patients significantly higher than in control group diagnosed by RTE (P = 0.001). There was an agreement between RTE and FIB-4 index (93%) and NAFLD fibrosis score (86%). Diagnostic performance of RTE in advanced liver fibrosis ≥ F3 was assessed in comparing with FIB-4 index show sensitivity 90%, specificity 93.3%, PPV 60%, NPV 98.8% and accuracy 93% with AUC0.917 (p = 0.001) and in comparing with NAFLD fibrosis score sensitivity 52.6%, specificity 93.8%, PPV 66.7%, NPV 98.4% and accuracy 86% with AUC 0.732 (p = 0.002). <b>Conclusion: </b>Real time elastography could be valuable in diagnosis of fibrosis in NAFLD especially in cases more than F3 score.
推荐文章
IQQA(R)-Liver系统术前评估对精准肝切除的意义
IQQA(R)-Liver分析系统
AW4.4工作站
精准肝切除
SimuLink Real Time的EtherCAT实时控制系统研发
EtherCAT
SimuLinkRealTime
实时控制
机器人控制
并联机器人
轨迹控制
Real Time PCR研究进展及其在海洋病原生物检测中的应用
Real Time PCR
SYBR Green Ⅰ
Taqman探针
多重实时定量PCR
内容分析
关键词云
关键词热度
相关文献总数  
(/次)
(/年)
文献信息
篇名 Real Time Elastography is an Easy Tool for Diagnosis of Liver Fibrosis in Non-Alcoholic Fatty Liver Disease
来源期刊 医学影像期刊(英文) 学科 医学
关键词 Non-Alcoholic Fatty Liver Disease Real Time Elastography FIB-4 Index NAFLD Fibrosis Score
年,卷(期) yxyxqkyw,(2) 所属期刊栏目
研究方向 页码范围 110-124
页数 15页 分类号 R57
字数 语种
DOI
五维指标
传播情况
(/次)
(/年)
引文网络
引文网络
二级参考文献  (0)
共引文献  (0)
参考文献  (0)
节点文献
引证文献  (0)
同被引文献  (0)
二级引证文献  (0)
2020(0)
  • 参考文献(0)
  • 二级参考文献(0)
  • 引证文献(0)
  • 二级引证文献(0)
研究主题发展历程
节点文献
Non-Alcoholic
Fatty
Liver
Disease
Real
Time
Elastography
FIB-4
Index
NAFLD
Fibrosis
Score
研究起点
研究来源
研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
医学影像期刊(英文)
季刊
2164-2788
武汉市江夏区汤逊湖北路38号光谷总部空间
出版文献量(篇)
25
总下载数(次)
0
论文1v1指导