<b><span style="font-family:Verdana;">Introduction</span></b><span style="font-family:;" "=""><span style="font-family:Verdana;">: With a considerable morbidity, mortality and a high financial impact, PJI has been considered as one of the most serious complications after arthroplasty. Special awareness must be given to these patients due to a life threatening systemic PJI related complication, sepsis. A prompt detection and adequate medical management of this situation is crucial for avoiding unfavorable outcomes. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> Between January 2011 and December 2012</span></span><span style="font-family:Verdana;">,</span><span style="font-family:;" "=""><span style="font-family:Verdana;"> we retrospectively examined adult patients who met PJI-SIRS criteria. Medi</span><span style="font-family:Verdana;">cal history search for patients’ anamnesis, surgical times, laborato</span><span style="font-family:Verdana;">ry-microbiological findings and success rates was performed. </span><b><span style="font-family:Verdana;">Results: </span></b><span style="font-family:Verdana;">Twenty patients were enrolled in this study with a mean age of 71.35 years. Men population was more commonly affected with 55% of the cases. The knee was mainly the affected joint with 52%. A severe systemic disease was present in 80% of the </span><span style="font-family:Verdana;">cases. A sickness sensation and pain were the most common prodromal</span><span> </span><span style="font-family:Verdana;">symp</span><span style="font-family:Verdana;">toms found 4.9 days before the admission to the hospital. In 85.7% of the</span><span style="font-family:Verdana;"> cases the etiological agent was identified, with </span><i><span style="font-family:Verdana;">Staphylococcus aureus</span></i><span style="font-family:Verdana;"> as the most common. Two</span></span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">stage surgery treatment was p