Morphological and Structural Study of Native Kidneys in Chronic Kidney Disease Patients on Dialysis Compared to Non-Dialysis Patients

• 作者: Bruno Leopold Agboton Hosana Kpoviessi SM Jacques Vigan Olivier Biaou Patricia Ahouansou Yekpe Séraphin Ahoui Sonia Adjanohoun
• 来源期刊: 肾脏病(英文)
• 学科: 医学
• 关键词: Chronic Kidney Disease DIALYSIS Acquired Renal Cysts
• 年，卷（期）: 2020,（4）
• 页码范围: 348-360
• 页数: 13页
• 分类号: R69

摘要

Whether on dialysis or not, native kidneys in chronic kidney disease (CKD) patients undergo morphological and structural changes. <strong>Objective:</strong> To study native kidney morphometric and structural aspects in CKD patients on dialysis and non-dialysis patients. <strong>Methods:</strong> It was a descriptive, analytical, and cross-sectional study conducted from May to December 2018. The study enrolled CKD patients on dialysis or not followed at CNHU-HKM in Cotonou. Renal ultrasound was performed to locate cysts and uroscanner completed in the presence of atypical cysts. Through logistic regression, associated factors were determined. <strong>Results:</strong> The sample size was 240 patients, of which 151 (62.9%) were receiving dialysis and 89 (37.1%) non-dialysis patients. Male subjects were predominant (sex ratio = 1.5). The average size of the right kidney, expressed in mm in patients on dialysis was: pole-to-pole length = 78.56;width = 42.06;cortical thickness = 11.80;and the left kidney: pole-to-pole length = 79.76;width = 41.53;cortical thickness = 12.6. For non-dialysis patients, the following size was recorded for the right kidney: pole-to-pole length = 92.35;width = 47.61;cortical thickness = 15.64;and left kidney: length = 92.13;width = 47.82;cortical thickness = 15.43. Predictive factors for the occurrence of acquired renal cysts were: old age (p = 0.0001), dialysis (p < 0.001) and diabetic nephropathy (p = 0.0014). <strong>Conclusion:</strong> CKD patients on dialysis have small kidneys and are more likely to develop acquired renal cysts. There is a need to carry out an annual ultrasound screening for native kidneys in patients receiving dialysis.