SCGN-regulated Stage-wise SNARE Assembly:Novel Insight into Synaptic Exocytosis

• 来源期刊: 神经科学通报（英文版）
• 年，卷（期）: 2020,（12）
• 所属期刊栏目: Research Highlights
• 页码范围: 1576-1578
• 页数: 3页
• 语种: 英文

摘要

In neuroendocrine cells,hormones and neuropeptides stored in secretory granules are released in response to various stimuli in a highly concerted process,including the sequential actions of vesicle trafficking,docking,fusion,and unloading.In this process,the crucial step of vesicle fusion requires the formation of a soluble N-ethyl-maleimide-sensitive factor attachment protein receptor(SNARE)complex,comprising primarily SNAP-25,syn-taxin 1,and synaptobrevin 2[1,2].