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摘要:
The mutations in ontogenes have been shown to drastically increase the nondisjunction of X chromosomes in the <i><span style="font-family:Verdana;">D. melanogaster</span></i><span style="font-family:Verdana;"> meiosis. This means that ontogenes are involved in the process that brings the homologs together although both the genes and ontogenes are finally paired. The phenomenon named the paradox of homologous pairing is described. Chromosomal rearrangements (inversions and translocations) lead to formation of specific topological figures (loops and crosses) during pairing. The mutual arrangement of the nucleotide sequences of homologous ontogenes before and after formation of such figures is different. Their arrangement coincides after a figure is formed and the pairing looks homologous. However, before the figure is formed, their arrangement does not match and the pairing is actually nonhomologous. The available data on ontogenes allows this paradox to be resolved. It is assumed that the sequence of each ontogene possesses a factor that 1) is a product of this nucleotide sequence;2) is co-located with this sequence;and 3) generates approaching independently of nucleotide sequence position in space. The sole candidate to the role of this factor is the DNA conformation of ontogene. The conformation in the form of a solenoid of DNA is able to generate</span><span style="font-family:Verdana;"> an</span><span style="font-family:Verdana;"> electromagnetic field independent of the orientation of the DNA itself. The proposed resolution of the paradox is considered in terms of the problem of genetic homology.</span>
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篇名 Ontogenes and the Paradox of Homologous Pairing
来源期刊 生命科学与技术进展(英文) 学科 物理学
关键词 Homologous Pairing MEIOSIS Ontogene DNA Conformation Electromagnetic Field DROSOPHILA
年,卷(期) 2021,(1) 所属期刊栏目
研究方向 页码范围 1-9
页数 9页 分类号 O57
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Homologous
Pairing
MEIOSIS
Ontogene
DNA
Conformation
Electromagnetic
Field
DROSOPHILA
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研究分支
研究去脉
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期刊影响力
生命科学与技术进展(英文)
月刊
2156-8456
武汉市江夏区汤逊湖北路38号光谷总部空间
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314
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0
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