Receptor-like kinases MDS1 and MDS2 promote SUMM2-mediated immunityFA

• 作者: Yanan Liu Xionghui Zhong Zhibin Zhang Jiameng Lan Xingchuan Huang Hainan Tian Xin Li Yuelin Zhang
• 来源期刊: 植物学报（英文版）
• 年，卷（期）: 2021,（2）
• 所属期刊栏目: Breakthrough Report
• 页码范围: 277-282
• 页数: 6页
• 语种: 英文

摘要

Disruption of the MEKK1-MKK1/MKK2-MPK4 kinase cascade leads to activation of immunity mediated by the nucleotide-binding leucine-rich repeat (NLR) immune receptor SUMM2, which monitors the phosphorylation status of CRCK3. Here we report that two receptor-like kinases (RLKs), MDS1, and MDS2, function redundantly to promote SUMM2-mediated immunity. Activation of SUMM2-mediated immunity is dependent on MDS1, and to a less extent on MDS2. MDS1 associates with CRCK3 in planta and can phosphorylate CRCK3 in vitro, suggesting that it may target CRCK3 to positively regulate SUMM2-mediated signaling. Our finding highlights a new defense mechanism where RLKs promote NLR-mediated immunity.