Propofol Protects Regulatory T Cells,Suppresses Neurotoxic Astrogliosis,and Potentiates Neurological Recovery After Ischemic Stroke

• 作者: Yuzhu Wang Dan Tian Yushang Zhao Mengyao Qu Yuhualei Pan Changwei Wei Yanbing Zhu Anshi Wu
• 来源期刊: 神经科学通报（英文版）
• 年，卷（期）: 2021,（5）
• 所属期刊栏目: Letters to the Editor
• 页码范围: 725-728
• 页数: 4页
• 语种: 英文

摘要

Dear Editor, Emergency intravascular thrombectomy is the best treat-ment for acute ischemic stroke[1].However,it is controversial whether the use of general anesthesia during emergency intravascular thrombectomy affects patient recovery.The most commonly-used intravenous anesthetic for emergency surgery is propofol.Previous studies from our team as well as others found that propofol reduces infarct size and potentiates neurological recovery in the early phase of ischemic stroke in mice[2-4].However,results from early time points do not fully reflect the influence of propofol on the dynamic progress of stroke.