Uncertainty principle plays an important role in multiple fields such as physics, mathem-atics, signal processing, etc. The linear canonical transform (LCT) has been used widely in optics and information processing and so on. In this paper, a few novel uncertainty inequalities on Fisher information associated with linear canonical transform are deduced. These newly deduced uncer-tainty relations not only introduce new physical interpretation in signal processing, but also build the relations between the uncertainty lower bounds and the LCT transform parameters a, b, c and d for the first time, which give us the new ideas for the analysis and potential applications. In addi-tion, these new uncertainty inequalities have sharper and tighter bounds which are the generalized versions of the traditional counterparts. Furthermore, some numeric examples are given to demon-strate the efficiency of these newly deduced uncertainty inequalities.