ZAR1 resistosome and helper NLRs:Bringing in calcium and inducing cell death

• 作者: Jian Chen Min Li Longyu Liu Gongyou Chen Zheng Qing Fu
• 来源期刊: 分子植物（英文版）
• 年，卷（期）: 2021,（8）
• 所属期刊栏目: Spotlights
• 页码范围: 1234-1236
• 页数: 3页
• 语种: 英文

摘要

To protect themselves from infectious diseases,plants have de-ployed a two-tiered surveillance system to recognize invading pathogens(Fu and Dong,2013).In the first layer of the immune system,plants evolved extracellular pattern recognition receptors to detect conserved pathogen-associated molecular patterns(PAMPs)and activate PAMP-triggered immunity(PTI)(Boller and Felix,2009).The second layer of the immune system,which is termed effector-triggered immunity(ETI),relies on an array of nucleotide-binding leucine-rich repeat receptor(NLR)proteins to detect pathogen effectors,either directly or the activities of these effectors indirectly(Figure 1A)(Sun et al.,2020).NLR activation often triggers a rapid localized cell death called hypersensitive response(HR).