Cold spray is an attractive and rapidly developing process for additive manufacturing with high efficiency and precision,repairing and coating,especially in aircraft and aerospace appli-cations.Cold spray additive manufacturing deposits micro-particles with large plastic deformation below their melting point,eliminating heat effect zone which could deteriorate the quality of repair-ing zone.The particle deposition in cold spray is a complex process which involves high strain rate,high contact pressure and high temperature.Here we develop,utilize and validate a thermo-mechanical model to provide a definitive way to predict deposition mechanics and surface deforma-tion evolution for particle deposition process in cold spray additive manufacturing.Both a single particle and dual particles models were developed to investigate the contact interaction between particle/substrate and particle/particle.Different combinations of particle/substrate materials(Cu/Cu,Al/Al,steel/steel,and nickel/nickel) and process parameters were considered in this study.The experimental study was conducted to validate simulation results,providing useful information for understanding the limitations and challenges associated with cold spray additive manufacturing.The framework provides insights into improving the quality and precision of stress/strain forma-tion,particle interactions and particle deposition in cold spray additive manufacturing process.